FB2024_03 , released June 25, 2024
Allele: Dmel\Adh+t11.8
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General Information
Symbol
Dmel\Adh+t11.8
Species
D. melanogaster
Name
FlyBase ID
FBal0038103
Feature type
allele
Associated gene
Dmel\Adh
Associated Insertion(s)
Carried in Construct
P{AP-2}
P{AP-5}
P{Sgs3.GA2.4}
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Goldberg et al., 1983)
wild_type
(Goldberg et al., 1983)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Goldberg et al., 1983)
wild_type
(Goldberg et al., 1983)
Mutagen
in vitro construct
(Martin et al., 1986, Posakony et al., 1985, Goldberg et al., 1983)
Progenitor genotype
AdhF
(Posakony et al., 1985)
Carried in construct
P{Adh11.8SacI}
P{AP-2}
P{AP-5}
P{Sgs3.GA2.4}
Cytology
Description

An 11.8kb SacI fragment that carries the AdhF allele. The AdhF gene is flanked by 6kb of DNA on the 5' side and 4kb on the 3'.

(Goldberg et al., 1983)
Allele components
Component
Use(s)
Regulatory region(s)
Adh
Encoded product / tool
Adh
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
2L:14,610,224..14,622,517 [+]
Linked to:
SstI-SstI restriction fragment
Comment:

Adh expression has correct tissue specificity and Adh protein levels. Position of restriction fragment on reference sequence inferred by FlyBase curator.

(Goldberg et al., 1983)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      enzyme assay or biochemical detection
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      larval stage
      posterior adult midgut progenitor
      (Goldberg et al., 1983)
      gastric caecum
      (Goldberg et al., 1983)
      embryonic/larval anterior midgut
      (Goldberg et al., 1983)
      fat body
      (Goldberg et al., 1983)
      somatic muscle cell
      (Goldberg et al., 1983)
      proventriculus | restricted
      (Goldberg et al., 1983)
      Malpighian tubule
      (Goldberg et al., 1983)
      adult stage | male
      seminal vesicle
      (Goldberg et al., 1983)
      vas deferens
      (Goldberg et al., 1983)
      northern blot
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      larval stage
      (Goldberg et al., 1983)
      adult stage
      (Goldberg et al., 1983)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Adh
      (Goldberg et al., 1983)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Adh expression has correct tissue specificity and Adh protein levels.

      (Posakony et al., 1985)

      Carried in a plasmid, expressed in E.coli cells and injected into preblastoderm embryos. Larvae and adults developed from these embryos are dissected and stained for Adh activity.

      (Martin et al., 1986)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Adh+t11.8
      Name Synonyms
      Secondary FlyBase IDs
        References (4)