FB2024_03 , released June 25, 2024
Allele: Dmel\nod9
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General Information
Symbol
Dmel\nod9
Species
D. melanogaster
Name
FlyBase ID
FBal0035281
Feature type
allele
Associated gene
Dmel\nod
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
natural population
(Zwick et al., 1999, Rasooly et al., 1994)
Progenitor genotype
Cytology
Description

Nucleotide substitution: G4515A, T4523A, T4524A and C4527G. Amino acid replacement: E?K. Nucleotide substitution: G4515A. Amino acid replacement: F?I. Nucleotide substitution: T4524A. Amino acid replacement: Q?E. Nucleotide substitution: C4527G.

(Zwick et al., 1999)

Gene conversion event as seen in noda resulting in 5 nucleotide changes.

(Rasooly et al., 1994)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
X:11,585,377..11,585,377 [+]
Nucleotide change:

T11585377A

Reported nucleotide change:

T4524A

Amino acid change:

F642I | nod-PA; F642I | nod-PB

Reported amino acid change:

F?I

Comment:

One of three amino acid substitutions in mutant. A silent substitution in L641 was also observed.

(Zwick et al., 1999)
point_mutation
X:11,585,368..11,585,368 [+]
Nucleotide change:

G11585368A

Reported nucleotide change:

G4515A

Amino acid change:

E639K | nod-PA; E639K | nod-PB

Reported amino acid change:

E?K

Comment:

One of three amino acid substitutions in mutant. A silent substitution in L641 was also observed.

(Zwick et al., 1999)
point_mutation
X:11,585,380..11,585,380 [+]
Nucleotide change:

C11585380G

Reported nucleotide change:

C4527G

Amino acid change:

Q643E | nod-PA; Q643E | nod-PB

Reported amino acid change:

Q?E

Comment:

One of three amino acid substitutions in mutant. A silent substitution in L641 was also observed.

(Zwick et al., 1999)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The frequency of X chromosome non-disjunction is increased in nod9 flies.

      (Zwick et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Weak nod allele.

      (Rasooly et al., 1994)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      nod9
      Name Synonyms
      Secondary FlyBase IDs
        References (2)