FB2024_03 , released June 25, 2024
Allele: Dmel\PT66D1.hs
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General Information
Symbol
Dmel\P\T66D1.hs
Species
D. melanogaster
Name
FlyBase ID
FBal0033939
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Associated Insertion(s)
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygotes are sterile. Progeny derived from mothers or fathers carrying the modified P-element exhibit a modest inhibitory effect of transposition in the soma and some repression of somatic P{hsP} excision events.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Lack of induction of repressing activity could be because heat shock in the eye disk destabilises both the transposase and 66kD protein. Homozygotes of the transposon are sterile but the sterility has not been shown to be due to the transposon itself. Other insertions of the transposons have a wild type phenotype and do not repress transposition of P{hsP}.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
P\T66D1.hs
Name Synonyms
Secondary FlyBase IDs
    References (1)