Nucleotide substitution: G2039A. Amino acid replacement: G535R.
G21556481A
G2039A
G535R | Egfr-PA; G584R | Egfr-PB
G535R
Homozygous adult semi-viable. In trans to Egfrt1, Egfrtop-ED16 shows unusually severe eye defects.
Adults exhibit more severe eye defects than would be expected from the wing and haltere defects. Embryos produced from heteroallelic combination with Egfrt1 have a severe ventralised phenotype, reduction in size of their dorsal appendage.
Mutation of Egfr that affects the gene function required for imaginal disc derivatives, a class IV lesion.
Class IV allele.