Nucleotide substitution: G2611A. Amino acid replacement: G702E.
G21557053A
G2611A
G702E | Egfr-PA; G751E | Egfr-PB
G702E
Lethality acts at embryonic and pupal stages. In trans to Egfrt1, Egfrtop-EA and Egfrtop-EB show unusually severe bristle defects.
Homozygous embryos show no defects, hemizygotes display a weak 'fkb' phenotype. Adults preferentially produce bristle defects. Embryos produced from heteroallelic combination with Egfrt1 have a severe ventralised phenotype, reduction in size of their dorsal appendage.
Mutation of Egfr that affects the gene function required for imaginal disc derivatives, a class IV lesion.
Class IV allele.