FB2024_03 , released June 25, 2024
Allele: Dmel\tllg
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General Information
Symbol
Dmel\tllg
Species
D. melanogaster
Name
FlyBase ID
FBal0032879
Feature type
allele
Associated gene
Dmel\tll
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
    Nature of the Allele
    Allele class

    loss of function allele

    (Eldon and Pirrotta, 1991)
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 1 )
        Disease
        Interaction
        References
        ameliorates  cancer
        modeled by AlkUAS.cLa
        (Wolfstetter et al., 2020)
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Most of the posterior gut regions fail to form in tllg mutants.

        (Uddin et al., 2011)

        Primordial germ cells exit the gut primordium normally in mutant embryos.

        (Jaglarz and Howard, 1994)

        hkbA, tllg double mutants show the same pattern of expression of a bcd promoter fragment-lacZ fusion gene as wild type, ruling out the involvement of hkb and tll products in setting its pattern of expression.

        (Ronchi et al., 1993)

        The posterior domain of gt never properly matures resulting in a shift of the fate map. The anterior domain of gt is not affected. In hkb2 tllg double mutant embryos the posterior border of gt stripe 4 retracts even less than in tllg mutants.

        (Eldon and Pirrotta, 1991)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        tllG
        (Uddin et al., 2011, Janody et al., 2000)
        tllg
        (Wolfstetter et al., 2020)
        Name Synonyms
        Secondary FlyBase IDs
          References (18)