Point mutation in the first zinc finger domain.
Nucleotide substitution: T1062A. This causes a cys to ser substitution within a 23 amino acid stretch in the N-terminal zinc finger.
T16039127A
T1062A
C190S | pnr-PA; C138S | pnr-PB; C190S | pnr-PC; C138S | pnr-PD
C?S
Position of mutation on reference sequence inferred by FlyBase curator based on author statement. (Figure 3 and Table 1)
Class A allele. Allelic series for dominant phenotype, going from greatest to least effect pnrD4 > pnrD1 > pnrD2 = pnrD3.
Class 4 pnr allele: dominant allele causing a gain of bristles. Allelic series according to the extent of the dorsal hole: pnr1 > Df(3R)sbd45 = pnrVX6 = pnrVP8 = pnrD1 > pnrD3.