FB2024_03 , released June 25, 2024
Allele: Dmel\Raf::torKV.13D.hs.sev
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General Information
Symbol
Dmel\Raf::torKV.13D.hs.sev
Species
D. melanogaster
Name
FlyBase ID
FBal0032424
Feature type
allele
Associated gene
Raf::tor
Associated Insertion(s)
Carried in Construct
P{sE-raftor4021KV}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Dickson et al., 1992)
Progenitor genotype
tor13D
(Dickson et al., 1992)
Carried in construct
P{sE-raftor4021KV}
Cytology
Description

Raf kinase domain, with a valine replacing the conserved lysine in the ATP binding site, fused to the signal sequence, intracellular and transmembrane domains carrying the amino acid replacement characteristic of the tor13D protein, expressed from the sev enhancer and a heat shock promoter.

(Dickson et al., 1992)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
sev
Encoded product / tool
Raf::tor
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Dominant eye phenotype of phl::tor13D.hs.sev alleviated.

      (Dickson et al., 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Demonstrates that dominant eye phenotype of phl::tor13D.hs.sev is caused through the action of the phl kinase.

      (Dickson et al., 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Raf::torKV.13D.hs.sev
      phl::torKV.13D.hs.sev
      Name Synonyms
      Secondary FlyBase IDs
        References (1)