FB2024_03 , released June 25, 2024
Allele: Dmel\ninaCKD
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General Information
Symbol
Dmel\ninaCKD
Species
D. melanogaster
Name
FlyBase ID
FBal0032279
Feature type
allele
Associated gene
Dmel\ninaC
Associated Insertion(s)
Carried in Construct
P{ninaCKD}
Also Known As
pninaC<up>KD</up>
Key Links
Transgenic product class
inframe_deletion
(Porter and Montell, 1993)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Porter and Montell, 1993)
Mutagen
in vitro construct
(Porter and Montell, 1993, Porter et al., 1993)
Progenitor genotype
ninaC+t4.0
(Porter and Montell, 1993)
Carried in construct
P{ninaCKD}
Cytology
Description

Deletion of the kinase domain (amino acids 17 to 284).

(Porter and Montell, 1993)
Allele components
Component
Use(s)
Regulatory region(s)
ninaC
Encoded product / tool
ninaC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ommatidia dissociated from flies carrying ninaCKD in a ninaC5 background show a loss of inactivation of activated-metarhodopsin, with the time constants of final response inactivation being indistinguishable in the presence or absence of Ca[2+].

      (Liu et al., 2008)

      The electroretinogram response of flies carrying ninaCKD in a ninaC5 background is abnormal.

      (Wes et al., 1999)

      Flies carrying ninaCKD in a ninaC5 background have an abnormal electroretinogram (ERG) that is distinct from that of ninaC5 flies. Flies carrying ninaCKD in a ninaC5 background do not show retinal degeneration.

      (Porter and Montell, 1993)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ninaCKD
      (Liu et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)