FB2024_03 , released June 25, 2024
Allele: Dmel\esgL7
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General Information
Symbol
Dmel\esgL7
Species
D. melanogaster
Name
FlyBase ID
FBal0031215
Feature type
allele
Associated gene
Dmel\esg
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Hayashi et al., 1993)
Mutagen
Delta2-3 transposase
(Hayashi et al., 1993)
P-element activity
(Ashburner et al., 1999.10.12)
Progenitor genotype
esgP2
(Hayashi et al., 1993)
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes have held-out wings, but are otherwise normal. Many heteroallelic combinations studied. Heterozygotes with esgGW2 and esgGW13 appear wild type. Heterozygotes with esgL2, esgL6 and Df(2L)A48 die as pharate adults that may have twisted legs.

      (Hayashi et al., 1993)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Designated "hypomorph" because esgL7 over Df(2L)A48 is pupal lethal whereas esgL7 homozygotes are viable.

      (Hayashi et al., 1993)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      esgL7
      Name Synonyms
      Secondary FlyBase IDs
        References (2)