FlyBase Allele Report: Dmel\bab2[E1]

General Information

Symbol

Dmel\bab2^E1

Species

D. melanogaster

Name

FlyBase ID

FBal0030542

Feature type

allele

Associated gene

Dmel\bab2

Associated Insertion(s)

Carried in Construct

Also Known As

bab^E1

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Godt et al., 1993)

Mutagen

ethyl methanesulfonate

(Godt et al., 1993)

Progenitor genotype

Cytology

Description

Mutation causes a severe reduction in the amount of bab2 protein produced.

(Couderc et al., 2002)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal body color | female | recessive

(Couderc et al., 2002)

female sterile | recessive

(Couderc et al., 2002, Godt et al., 1993)

visible | dominant

(Godt et al., 1993)

visible | recessive

(Couderc et al., 2002, Godt et al., 1993)

Phenotype Manifest In

abdominal tergite 5 | female

(Couderc et al., 2002)

abdominal tergite 6 | female

(Couderc et al., 2002)

antenna

(Godt et al., 1993)

leg

(Couderc et al., 2002, Godt et al., 1993)

ovariole

(Couderc et al., 2002)

ovary

(Couderc et al., 2002, Godt et al., 1993)

prothoracic tarsal segment 2

(Godt et al., 1993)

Detailed Description

Statement

Reference

Homozygous females have a strong mutant ovary phenotype; the ovaries are very small and contain only 1-2 ovarioles of very abnormal structure and orientation and the females do not lay eggs. Homozygotes have a strong mutant leg phenotype. Homozygous females show uniformly dark pigmentation of the A5 and A6 tergites.

(Couderc et al., 2002)

Ectopic sex comb on tarsal segment 2.

(Godt et al., 1993)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

bab2^E3

(Couderc et al., 2002)

bab2^E6

(Couderc et al., 2002)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

66681

bab2^E1 st¹ e^*/TM6B, Tb¹ ca¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

bab2^E1

(Junion et al., 2007)

bab^E1

(Bartoletti et al., 2012, Couderc et al., 2002)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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