FB2024_03 , released June 25, 2024
Allele: Dmel\PTKP
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General Information
Symbol
Dmel\P\TKP
Species
D. melanogaster
Name
KP-element
FlyBase ID
FBal0030011
Feature type
allele
Associated gene
P\T
Associated Insertion(s)
Carried in Construct
P{KP}
Also Known As
KP
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
natural population
(Lee et al., 1996)
in vitro construct
(Lemaitre et al., 1993, Itoh et al., 1988)
Progenitor genotype
Carried in construct
P{KP}
Cytology
Description

207 amino acid P-element due to an internal deletion.

(Lee et al., 1996)

Internal deletion of the P-element.

(Gloor et al., 1993)

P\T sequences deleted between nucleotide 807 and 2561.

(Ito et al., 1993)

Deletion of nucleotides 809 to 2559.

(Lemaitre et al., 1993)

Deletion from 808bp to 2560bp.

(Heath and Simmons, 1991)

Defective 1.15kb P-element.

(Ito et al., 1989)

Defective P-element : deletion from base 808 to base 2560.

(Itoh et al., 1988)

Construct: Internal deletion of 1753bp removing nucleotides 808 to 2560.

(Black et al., 1987)
Allele components
Component
Use(s)
Encoded product / tool
P\T
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      northern blot
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      adult
      (Black et al., 1987)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Repression of P-element mobility in somatic tissues.

      (Lemaitre et al., 1993)

      Individuals that carry a copy of P\TKP on the second chromosome have suppressed P-element susceptibility due to the repression of P-element transcription.

      (Higuet et al., 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      Comments
      Comments

      KP elements preferentially accumulate in the presence of P-elements and suppress hybrid dysgenesis in both sexes. Strains lacking the P cytotype (M') contain up to 30 copies of KP-element per haploid genome.

      (Black et al., 1987)

      Type I element.

      (Corish et al., 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      KP
      (Bonnivard and Higuet, 1999, Heath and Simmons, 1991, Raymond et al., 1991)
      P\TKP
      Name Synonyms
      KP-element
      (Black et al., 1987)
      Secondary FlyBase IDs
        References (26)