FB2024_03 , released June 25, 2024
Allele: Dmel\yl15
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General Information
Symbol
Dmel\yl15
Species
D. melanogaster
Name
FlyBase ID
FBal0018791
Feature type
allele
Associated gene
Dmel\yl
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      There is a 2.55-fold reduction in the number of clathrin-coated pits and vesicles in oocytes of yl15 females.

      yl15 oocytes grow normally during development.

      (Sommer et al., 2005)

      Strong phenotype. Oocytes produced by homozygous females contain fewer proteinaceous yolk spheres than oocytes produced by wild-type females. These abnormal yolk spheres do contain some yolk. The adult hemolymph of homozygous females contains a much higher level of vitellogenin than normal.

      (DiMario and Mahowald, 1987)

      Eggs that are laid lack proteinaceous yolk and collapse due to fragile chorion.

      (Mohler and Carroll, 1984)

      female-sterile

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      11-380
      (DiMario and Mahowald, 1987)
      fs(1)11-380
      fs(1)M2511-380
      (Mohler and Carroll, 1984)
      yl15
      (Sommer et al., 2005)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)