FB2024_03 , released June 25, 2024
Allele: Dmel\Su(var)3-321
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General Information
Symbol
Dmel\Su(var)3-321
Species
D. melanogaster
Name
FlyBase ID
FBal0016542
Feature type
allele
Associated gene
Dmel\Su(var)3-3
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Reuter et al., 1986)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heterozygotes show an increase in crossing over between kni and pp.

      (Westphal and Reuter, 2002)

      Strongly semi-lethal in homozygous males, weakly semi-lethal in homozygous females. Homozygous females are sterile and do not produce any eggs. Homozygous males have a spread-wing phenotype, and strongly reduced fertility. Dominant suppressor of position effect variegation at the w locus caused by In(1)wm4h.

      (Reuter et al., 1986)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Isolated as a suppressor of position effect variegation at the w locus in flies carrying In(1)wm4h, and a dominant enhancer of position effect variegation, E(var)c1011.

      (Reuter et al., 1986)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      SU(VAR)3-321
      (Rudolph et al., 2007)
      Su(var)3-321
      lsd121
      (Lee and Spradling, 2014)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)