FB2024_03 , released June 25, 2024
Allele: Dmel\sc3B
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General Information
Symbol
Dmel\sc3B
Species
D. melanogaster
Name
3 of Bridges
FlyBase ID
FBal0015192
Feature type
allele
Associated gene
Dmel\sc
Associated Insertion(s)
gypsy{}sc3B
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
(Campuzano et al., 1985)
Progenitor genotype
Associated Insertion(s)
gypsy{}sc3B
Cytology
Description

Distalmost part of the achaete-scute complex is disconnected from the coding region of ac by a gypsy transposable element.

(Ruiz-Gomez and Ghysen, 1993)

Insertion of gypsy element.

(Georgiev and Gerasimova, 1989)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies show a loss or reduction in the number of scutellar, anterior dorsocentral, first and second orbital, ocellar and some other bristles. Pigmentation is normal. The phenotype is affected by mod(mdg4)ul; the ocellar, first and second orbital bristles are present, while the dorsocentral bristles are lost completely. Hairs and bristles are yellow.

      (Georgiev and Gerasimova, 1989)

      Like sc but does not affect anterior notopleurals. Suppressed by su(Hw)2 (Lee, 1973). RK1. Some stocks currently labelled sc3B are reverted for sc but are now ac3B.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (1)
      Stocks (1)
      Notes on Origin
      Discoverer

      Bridges, 26th April 1926.

      Comments
      Comments

      Molecular data suggests that the original sc3B chromosome had a complete gypsy inserted in the scute β region. Later this gypsy is excised, leaving behind its LTR. Another mutational event inserted a second gypsy in the ac region, explaining the present ac phenotype.

      (Campuzano et al., 1985)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      sc3B
      Name Synonyms
      3 of Bridges
      Secondary FlyBase IDs
        References (8)