FB2024_03 , released June 25, 2024
Allele: Dmel\paraST42
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General Information
Symbol
Dmel\paraST42
Species
D. melanogaster
Name
FlyBase ID
FBal0013484
Feature type
allele
Associated gene
Dmel\para
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Pittendrigh et al., 1997)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      paraST42 mutant larvae display modest resistance to picrotoxin (PTX)-induced seizures.

      (Stilwell et al., 2006)

      Homozygous flies do not show significant resistance to dichloro-diphenyl-trichloro ethane (DDT) compared to wild-type flies.

      (Pittendrigh et al., 1997)

      Reversible heat induced paralysis.

      (Siddiqi and Benzer, 1976)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Results from response to cervical stimulation, intracellular recordings of flight muscles and direct excitability of muscle demonstrate the threshold for excitability of a cervical pathway rises at temperatures a few degrees higher than the paralysis temperature while nerve conduction velocity and muscle excitability are still normal.

      (Siddiqi and Benzer, 1976)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      paraST42
      (Stilwell et al., 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)