FB2024_03 , released June 25, 2024
Allele: Dmel\otuPΔ4
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General Information
Symbol
Dmel\otuPΔ4
Species
D. melanogaster
Name
FlyBase ID
FBal0013370
Feature type
allele
Associated gene
Dmel\otu
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
PM hybrid dysgenesis
(Geyer et al., 1993, Sass et al., 1993)
Progenitor genotype
otu20
(Geyer et al., 1993, Sass et al., 1993)
Cytology
Description

2.3kb deletion extending from -732bp to +1612bp (of Comer et al., Gene 118:171-179 ). Deletion removes P element, 5' regulatory sequences, the first four exons and most of the fifth exon of otu.

(Geyer et al., 1993)

Deletion of approximately 2.6kb removing sequences both upstream and downstream of the parental P element insertion site. The downstream deletion endpoint is within the otu coding region.

(Sass et al., 1993)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
X:8,487,884..8,490,226 [-]
Comment:

2.3kb deletion extending from -732bp to +1612bp

(Geyer et al., 1993)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Substantial proportion of ovarioles lack egg cysts.

      (Geyer et al., 1993)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      QUI class allele.

      (Sass et al., 1993)

      QUI class allele. Phenotype is more severe than for deletion of the otu locus.

      (Geyer et al., 1993)

      Shows a dominant interaction with ovoD2 and ovoD3 : more extreme mutant phenotype as assayed by reduction in number of egg chambers at stage 10 or further developed. There is no apparent correlation with strength of otu allele and its interaction with the ovo alleles.

      (Pauli et al., 1993)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      otuPd4
      (Pauli et al., 1993)
      otuPΔ4
      Name Synonyms
      Secondary FlyBase IDs
        References (4)