FB2024_03 , released June 25, 2024
Allele: Dmel\Nnd-0
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General Information
Symbol
Dmel\Nnd-0
Species
D. melanogaster
Name
FlyBase ID
FBal0012889
Feature type
allele
Associated gene
Dmel\N
Associated Insertion(s)
Carried in Construct
Also Known As
fan
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Glass, 1933)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Dp(2;Y)G44 males crossed to a stock carrying Nspl-1 produce sons that have straight wings or curly wings. Curly wings result from trisomy for the 44C--50B region: enhance the mutant effect of Nnd-0.

      (Birchler, 1988)

      Wings have small notches at their apical ends in nearly all males, but only in 8% of homozygous females. Nnd-0/Df(1)N-8 flies lack considerable portions of the apical region of the wing and large portions of the costal vein and anterior wing margin, while in some cases portions of the posterior wing margin are also missing. The eyes are slightly roughened. Nnd-0/Nfa-1 is phenotypically normal, except in very rare cases (0.26%) where slight notches in the wing are seen.

      (Glass, 1933)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      N264-8

      (Slizynska, 1938)

      N264-39

      (Slizynska, 1938)
      Comments

      The allele has not been separated from the inversion.

      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Glass, 1929.

      Induced on: In(1)dl-49.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      Nnd-0
      (Casso et al., 2011)
      Nnd0
      (Rice et al., 2015)
      fan
      (Lloyd, 2000, Heitzler, 1997, Slizynska, 1938, Glass, 1933)
      nd
      (Birchler, 1988)
      nd0
      Name Synonyms
      facet-notched
      Secondary FlyBase IDs
        References (8)