Polytene chromosomes normal.
8kb deletion extending from an intronic region, between exons 4 and 5, to a site approximately 2.5kb distal to the end of the transcription unit. The predicted protein encodes a truncated 923 amino acid protein.
No P-element detectable by in situ hybridisation. Deletion of approximately 12kb.
Embryonic CNS exhibits moderate-severe disturbances and larval exhibit moderate cuticle loss.
Larvae have variable cuticular abnormalities, including the absence of large portions of the cephalic and ventral epidermis. The anterior end of the embryo is filled with neural cells and the ventral nerve cord is expanded.
P-element or transposase source: Harwich P strain.