FB2024_03 , released June 25, 2024
Allele: Dmel\hb10
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General Information
Symbol
Dmel\hb10
Species
D. melanogaster
Name
FlyBase ID
FBal0005401
Feature type
allele
Associated gene
Dmel\hb
Associated Insertion(s)
Carried in Construct
Also Known As
hb11C
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Hulskamp et al., 1994)
Mutagen
ethyl methanesulfonate
(Hulskamp et al., 1994, Lehmann and Nusslein-Volhard, 1987, Tearle and Nusslein-Volhard, 1987)
Progenitor genotype
Cytology
Description

Amino acid replacement: C738R. Nucleotide substitution: TGC to CGC. C738 lies within the second zinc finger domain.

(Hulskamp et al., 1994)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:8,691,943..8,691,943 [-]
Nucleotide change:

T8691943C

Reported nucleotide change:

T?C

Amino acid change:

C738R | hb-PA; C738R | hb-PB

Reported amino acid change:

C738R

(Hulskamp et al., 1994)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The second and third thoracic segments are missing.

      (Hulskamp et al., 1994)

      Retains prothoracic and A7 segments

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Class II allele.

      Phenotypic class I.

      (Lehmann and Nusslein-Volhard, 1987)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      hb10
      hb11C
      (Hulskamp et al., 1994, Lehmann and Nusslein-Volhard, 1987, Tearle and Nusslein-Volhard, 1987)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)