FB2024_03 , released June 25, 2024
Allele: Dmel\dsxT
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General Information
Symbol
Dmel\dsxT
Species
D. melanogaster
Name
FlyBase ID
FBal0003205
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Progenitor genotype
Associated Insertion(s)
Cytology
Description

Insertion of a 4.5kb middle repetitive element 127bp 3' of the female-specific splice acceptor site and within the female-specific exon.

Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

No more than 26% of XX dsxT/dsx1 mutant pseudomales produce gonads with the most severe group 1 pseudotestes phenotype. The remaining pseudomales have a less severe phenotype, with viable germ cells. otu10 and Df(1)otu-PΔ1 cause an increase in severity of this phenotype: over 70% of the resulting gonads were of group 1.

Only affects XX flies: the terminalia of XX heterozygous flies carry abnormal male and female elements, with the female genitalia anterior to the male genitalia. The male genitalia are well developed, but the penis apparatus is reduced, the hypandrium is mostly absent and many bristles are abnormal. The female vaginal plate is always present, but is reduced in size with abnormal bristles. There is often a mass of yellow, chitinised material between the vaginal plates, which is a secondary rudimentary penis apparatus. The anal plates have a sexually intermediate shape, and a bristle pattern which is a mosaic of male, female and intermediate bristles. The basitarsus of the foreleg carries a sex comb whose position and shape are intermediate between male and female. XX hemizygotes are sterile pseudomales.

External Data
Interactions
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Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
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Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Gehring.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
dsxT
Name Synonyms
Secondary FlyBase IDs
    References (5)