FB2024_03 , released June 25, 2024
Allele: Dmel\dsxS
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General Information
Symbol
Dmel\dsxS
Species
D. melanogaster
Name
FlyBase ID
FBal0003203
Feature type
allele
Associated gene
Dmel\dsx
Associated Insertion(s)
Carried in Construct
Also Known As
dsxSWE
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Nagoshi and Baker, 1990, Baker and Wolfner, 1988)
Progenitor genotype
Cytology
Description

448bp deletion associated with the addition of 5 bases (CCAAA). The 5' breakpoint of the deletion is 108bp 3' of the female-specific splice acceptor site.

(Nagoshi and Baker, 1990)

Deletion of 0.6kb DNA within region important for regulation of dsx expression.

(Baker and Wolfner, 1988)

small deletion in female exon

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
3R:7,935,082..7,935,538 [-]
Inserted_sequence:

CCAAA

Comment:

Reported as a deletion of 448bp associated with the insertion of 5 bases (CCAAA) at the deletion breakpoint. The mutation falls within the female-specific exon.

(Nagoshi and Baker, 1990)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      XX dsxS/dsx43 animals develop as pseudomales.

      (Waterbury et al., 2000)

      Egg chambers of dsxS/+ females appear normal. When heterozygous with a deficiency, pseudotestes form.

      (Horabin et al., 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Brandt-Rosequist.

      Comments
      Comments

      Results in a male specific dsx+ RNA, thus can be used to generate 2X males.

      (Oliver et al., 1993)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      dsxS
      dsxSWE
      (Dauwalder et al., 2002)
      dsxSwe
      (Rideout et al., 2010, Andrews and Oliver, 2002, Waterbury et al., 2000, Waterbury et al., 1999, Horabin et al., 1995)
      dsxswe
      (Oliver et al., 1993)
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0031142
      References (9)