Amino acid replacement: G402E. Nucleotide substitution: GGA to GAA.
G9408789A
G?A
G402E | betaTub85D-PA
G402E
microtubule & testis
The testes of homozygous males are characterised by complete lack of microtubule-dependent function in the postmitotic germ cells. There is also no evidence of meiotic spindle activity, the spermatid nuclei remain 4N and the spermatid head remains unshaped. The spermatid fails to elongate.
Class I allele.