FB2024_04 , released June 25, 2024
Aberration: Dmel\Df(1)YO17
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General Information
Symbol
Df(1)YO17
Species
D. melanogaster
Name
FlyBase ID
FBab0047482
Feature type
Computed Breakpoints include
Sequence coordinates
X:16,628,082..16,628,082 (Df(1)YO17:bk1)
X:16,640,997..16,640,997 (Df(1)YO17:bk2)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

Encompasses the promoter, upstream regulatory region and part of the 5' UTR of mthl1, as well as the coding regions of SmG, RpS19a, CG9777 and rok.

Imprecise excision of the progenitor insertion, resulting in a deletion which extends from 14F2, X:16522115 (release 5 coordinates) to the the P{EPgy2}mthl1EY16157 insertion site at 14F4, X:16535030 (release 5 coordinates). A portion of the original insertion, from nucleotide 6624 to the 3' P-element end remains associated with the deletion. The right breakpoint is within mthl1, generating the mthl1YO17 allele.

Comments on Cytology
Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
Phenotypic Data
In combination with other aberrations

Heterozygosity for Df(1)YO17 leads to a high frequency of defects in leg morphogenesis.

Zygotically embryonic lethal. Mutant embryos have uncoordinated ventral furrow apical constriction. Embryos exhibit defects in internalization of mesodermal cells or changes to the morphology of the ventral midline.

NOT in combination with other aberrations

Heterozygous females show a Minute phenotype (due to the deletion of RpS19a) and do not eclose well at 18[o].

Stocks (1)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)