Imprecise excision of the progenitor insertion, resulting in a deletion which extends from 14F2, X:16522115 (release 5 coordinates) to the the P{EPgy2}mthl1EY16157 insertion site at 14F4, X:16535030 (release 5 coordinates). A portion of the original insertion, from nucleotide 6624 to the 3' P-element end remains associated with the deletion. The right breakpoint is within mthl1, generating the mthl1YO17 allele.
Heterozygosity for Df(1)YO17 leads to a high frequency of defects in leg morphogenesis.
Zygotically embryonic lethal. Mutant embryos have uncoordinated ventral furrow apical constriction. Embryos exhibit defects in internalization of mesodermal cells or changes to the morphology of the ventral midline.
Heterozygous females show a Minute phenotype (due to the deletion of RpS19a) and do not eclose well at 18[o].