FB2024_04 , released June 25, 2024
Aberration: Dmel\Df(3R)E(spl)δ-6
Open Close
General Information
Symbol
Df(3R)E(spl)δ-6
Species
D. melanogaster
Name
FlyBase ID
FBab0046895
Feature type
chromosomal_deletion
Also Known As
E(spl)-CΔmδ-m6
Computed Breakpoints include
Features within 96F9--96F10 (Estimated cytology)
Genomic Maps
Sequence coordinates
3R:25,995,606..25,995,606 (Df(3R)E(spl)delta-6:bk1)
(Chanet et al., 2009)
3R:26,036,959..26,036,959 (Df(3R)E(spl)delta-6:bk2)
(Chanet et al., 2009)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
P{XP}d08311
(Chanet et al., 2009)
PBac{RB}Nf1e00084
(Chanet et al., 2009)
Mutagen
FLPase
(Chanet et al., 2009)
Class of aberration (relative to wild type)
chromosomal_deletion
(Chanet et al., 2009)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Chanet et al., 2009)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

Df(3R)E(spl)δ-6 removes promoter sequence from HLHm7, but leaves the coding sequence intact.

(Bardin et al., 2010)

Scer\FLP1-mediated recombination between the two progenitor insertions has resulted in a 41kb deletion.

(Chanet et al., 2009)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
Phenotypic Data
In combination with other aberrations

Stage 9/10 Df(3L)Brd-C1/Df(3R)E(spl)δ-6 transheterozygous embryos display loss of apical-basal cell polarity and of epithelial integrity; both of these defects are rescued by sdtΔ3-GFP but not by sdtGFP3.

(Perez-Mockus et al., 2017)

Df(3R)BSC751/Df(3R)E(spl)δ-6, Df(3R)ED6232/Df(3R)E(spl)δ-6, or Df(3R)E(spl)δ-6/Df(3R)Exel6204 mutant embryos display a significant increase in the number of Ap neurons, as compared with controls.

(Bivik et al., 2016)

Df(3R)E(spl)δ-6/Df(3R)grob32.2, in combination with gro+t10.4, mutant embryos display a significant increase in the number of Ap neurons, as compared with controls.

(Bivik et al., 2016)

39% of embryos homozygous for the Df(3L)Brd-C1 and Df(3R)E(spl)δ-6 deletions and carrying one copy of Dp(3;2)E(spl)δ-8 fail to hatch and only 2% reach pupal stages.

(Chanet et al., 2009)

Df(3R)E(spl)δ-6 Dp(3;2)E(spl)δ-8Δα46 double mutant flies do not show defects in bristle development.

(Chanet et al., 2009)

Df(3R)E(spl)δ-6/Dp(3;2)E(spl)δ-8 embryos are able to hatch.

(Chanet et al., 2009)

Dp(3;2)E(spl)δ-8Δα46 rescues the neurogenic phenotype associated with Df(3R)E(spl)δ-6.

(Chanet et al., 2009)

Animals homozygous for the Df(3L)Brd-C1 and Df(3R)E(spl)δ-6 deletions and carrying one copy of Dp(3;2)E(spl)δ-8Δα46 are 100% embryonic lethal.

(Chanet et al., 2009)

Flies homozygous for Df(3R)E(spl)δ-6 and carrying one copy of Dp(3;2)E(spl)δ-8Δα46 are viable and fertile with no detectable mutant morphological phenotype.

(Chanet et al., 2009)
NOT in combination with other aberrations

Df(3R)E(spl)δ-6/Df(3R)E(spl)δ-6 mutant embryos display a significant increase in the number of Ap neurons, as compared with controls.

(Bivik et al., 2016)

Homozygous intestinal stem cell (ISC) clones show an overproliferation of small ISC-like cells. The density and specification of large polyploid enterocytes is unaffected.

(Bardin et al., 2010)

Mutant embryos have a strong neurogenic phenotype.

(Chanet et al., 2009)
Stocks (0)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (6)
Reported As
Symbol Synonym
Df(3) E(spl)δ-6
(Perez-Mockus et al., 2017)
Df(3)E(spl)delta-6
(Caygill and Brand, 2017)
Df(3)E(spl)δ-6
(Chanet et al., 2009)
Df(3)mδ-m6
(Couturier et al., 2019)
Df(3R)E(spl)δ-6
E(spl)-CΔmδ-m6
(Bivik et al., 2016, Bardin et al., 2010)
Name Synonyms
Secondary FlyBase IDs
    References (6)