FB2024_03 , released June 25, 2024
Aberration: Dmel\In(1)FM6
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General Information
Symbol
In(1)FM6
Species
D. melanogaster
Name
FlyBase ID
FBab0003928
Feature type
chromosomal_inversion
Also Known As
FM6
Computed Breakpoints include

15D-15E;20F

Sequence coordinates
X:17,025,270..17,025,270 (In(1)FM6:bk1)
(Miller et al., 2016)
X:21,368,973..23,542,271 (In(1)FM6:bk2)
(Miller et al., 2016)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order

1Lt - 1B2 | (20B - 20B) | 15E - 20A | 15D - 11F4 | (4E - 4E) | 3C - 4D7 | 11F2 - 4F | 3C - 1B3 | 20D1 - 1Rt

(Slobodyanyuk and Serov, 1983)
Progenitor
In(1)FM4
(Merriam, 2017)
Mutagen
X ray
Class of aberration (relative to wild type)
chromosomal_inversion
Class of aberration (relative to progenitor)
Breakpoints

1B2-1B3;3C;4D7-4E;4E-4F;11F2-11F4;15D-15E;20A-20B;20B-20D1

(Slobodyanyuk and Serov, 1983)
Causes alleles
CG45002FM6
(Miller et al., 2016)
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

The 5' (distal) end of this breakpoint corresponds to X:17 ,025,270 and the 3' (proximal) end corresponds to X:17 ,025,272 (release 6 coordinates). This breakpoint is associated with a 1bp deletion. (FlyBase curator comment: coordinates updated from release 5 coordinates of X:16 ,919,303..16,919,305 given in paper.)

(Miller et al., 2016)

This breakpoint contains sequence from the transposable element HMS-Beagle and 18SrRNA sequence, consistent with the proximal breakpoint being in X chromosome centric heterochromatin and suggesting either a complex breakage/repair event following irradiation or postinversion rearrangement of sequences. (FlyBase curator comment: the coordinates used for this breakpoint correspond to the distal coordinate of the heterochromatin border defined in FlyBase (from FBrf0213099) through to the end of the sequenced chromosome.)

(Miller et al., 2016)
Comments on Cytology

Limits of break 1 from polytene analysis (FBrf0039957) Limits of break 2 from polytene analysis (FBrf0039957)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
CG45002
(Miller et al., 2016)
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In this case, the "Export to Hitlist" button at left will also be disabled.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Enhances the expression of PgdA in larvae and adults.

    (Slobodyanyuk and Serov, 1983)
    Stocks (0)
    Notes on Origin
    Discoverer

    R. F. Grell, Sep. 1955.

     
    Balancer / Genotype Variants of the Aberration
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    FM6
    (Miller et al., 2016, Durica and Krider, 1978)
    In(1)FM6
    (Miller et al., 2016)
    Name Synonyms
    Secondary FlyBase IDs
      References (18)