FB2024_03 , released June 25, 2024
Aberration: Dmel\Df(1)N-81l6
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General Information
Symbol
Df(1)N-81l6
Species
D. melanogaster
Name
Deficiency (1) Notch
FlyBase ID
FBab0000582
Feature type
chromosomal_deletion
Also Known As
N81l6
Computed Breakpoints include

3C7;3D2-3D3

Features within 3C7--3D3
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
(Grimwade et al., 1985, Artavanis-Tsakonas et al., 1983)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Levine et al., 1994, Grimwade et al., 1985)
Breakpoints

3C7-3C9;3D2-3D3

(Grimwade et al., 1985)

3C7-3C9;3E2-3E3

(Levine et al., 1994)
Causes alleles
dnc81l6
(Qiu and Davis, 1993)
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << N << bk2 hits dnc

Genetic mapping information
Comments

The proximal deletion breakpoint breaks within the dnc transcription unit removing the transcription start sites 1, 2, 3, 4 and 5.

(Qiu and Davis, 1993)

Breakpoint(s) molecularly mapped

(Chen et al., 1986)

-14.8 to -9.5 kb The zero coordinate used in locating the molecular lesions in the Notch deficiencies is the first Eco R1 site in Canton-S DNA proximal to the 3C7 breakpoint of In(1)N76b8 (Kidd et al., 1983); it is 1.1 kb to the right of the zero coordinate used by Artavanis-Tsakonas et al., 1983

Comments on Cytology

Band 3C7 is not completely deleted, but appears thinner than normal, suggesting it is partly deleted.

(Grimwade et al., 1985)

Left limit of break 1 from polytene analysis (FBrf0042381) Right limit of break 1 from inclusion of N (FBrf0042381) Limits of break 2 from polytene analysis (FBrf0042381)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
dnc
(Levine et al., 1994)
N
(Grimwade et al., 1985)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In this case, the "Export to Hitlist" button at left will also be disabled.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Homozygotes die as embryos. Heterozygotes show notching of the wing.

    (Grimwade et al., 1985)
    Stocks (0)
    Notes on Origin
    Discoverer

    Muskavitch.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (4)
    Reported As
    Symbol Synonym
    Df(1)N-81l6
    Df(1)N81l6
    (Levine et al., 1994)
    N81l6
    (Kooh et al., 1993, Grimwade et al., 1985, Artavanis-Tsakonas et al., 1983)
    Name Synonyms
    Deficiency (1) Notch
    Secondary FlyBase IDs
      References (8)