3C7;3C10-3C12
3C7;3C10-3C12
bk2 hits dnc
The proximal deletion breakpoint breaks within the dnc transcription unit removing the transcription start sites 1 and 2.
see Grimwade et al., Dev. Biol. 107: 503. The zero coordinate used in locating the molecular lesions in the Notch deficiencies is the first Eco R1 site in Canton-S DNA proximal to the 3C7 breakpoint of In(1)N76b8 (Kidd et al., 1983); it is 1.1 kb to the right of the zero coordinate used by Artavanis-Tsakonas et al., 1983
Welshons.
All limits from polytene analysis (FBrf0040118)