Male fertile.
Provides all of chromosome 3 necessary for normal development. C(3)EN-bearing flies produce two types of meiotic products with respect to chromosome 3: half disomic and half nullosomic; accordingly crosses to normal diploids produce only inviable mono- and triplo-3 zygotes; however crosses of C(3)EN flies to each other produce progeny. Transmission of C(3)EN by males versus that from females varies widely depending on the particular isolations tested, from 40% relative maternal transmission in some crosses through equal recovery in others, to 30% relative paternal transmission in yet others. In general these chromosomes perform poorly in stocks and crosses.
Synthesized by first selecting a T(Y;3) with a break in YL of BSYy+ and an absolutely terminal break in 3L. Females heterozygous for BSYL3L.3R and a normal third chromosome were irradiated and crossed to F(3L)/F(3L)/C(3R)RM males; one of the few surviving products of this cross is non-Bar and comes from fertilization of an ovum containing a half translocation between the base of 3R of the normal third and the distal YL material of the Dp(Y;3) fertilized by a sperm containing F(3L) but no C(3R); the F(3L) in this case was the YP3LD of a T(Y;3) involving breaks in YL of BSYy+ and the proximal heterochromatin of 3L, so that the desired survivor is 3R.3L3R/y+YS.3L in constitution. One product of recombination between 3L's in females of the above constitution is y+YS.3L3R. Females homozygous for the latter derivative were irradiated and crossed to C(3L)RM; C(3R)RM males; surviving y offspring carried 3R3L.3L3R = C(3)EN from the mother and no third chromosomal elements from the father. In situ hybridization with telomeric sequences provides no evidence for the presence of such sequences at the 3L - 3R junction (Goldstein, Barry and Novitski, 1981).
C(3)EN, 3R3L.3L3R