FB2024_04 , released June 25, 2024
Experimental tool: Tag:PM(hKRAS)
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General Information
Symbol
Tag:PM(hKRAS)
FlyBase ID
FBto0000256
Name
Plasma membrane targeting sequence of hKRAS
Description
Description

Plasma membrane localization signal, KMSKDGKKKKKKSKTKCVIM, corresponding to the C-terminal 20 amino acids of the 4B isoform of the Homo sapiens KRAS gene. This sequence consists of a polybasic domain comprising six consecutive Lys residues plus a prenylation signal (C-terminal CAAX motif), which are both required to target the protein to the plasma membrane (PMID:8196769, PMID:1756714, PMID:10412982).

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Transgenic Constructs
Encodes tool (1)
Transgenic construct(s)
Component allele
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Stocks
Tagged with the tool (25)
Transgenic construct(s)
Component allele
Reg. region
Encoded product / tool
Tagged with
Also carries
Stocks
Insertions ( 0 )
Synonyms and Secondary IDs (6)
Reported As
Symbol Synonym
T:Hsap\CAAX
Tag:PM(hKRAS)
Name Synonyms
Plasma membrane targeting sequence of hKRAS
Secondary FlyBase IDs
  • FBgn0017481
References (18)