LKAP
post-transcriptional effector domain that recruits CCR4-NOT deadenylase complex to shorten target mRNA poly-A tails and suppress their translation - ensures proper oocyte maturation by regulating nanos expression - transition from meiosis I to II is compromised mutant oocytes
Please see the JBrowse view of Dmel\Marf1 for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Transposon inserted in intron
Gene model reviewed during 5.47
Low-frequency RNA-Seq exon junction(s) not annotated.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Marf1 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: maternally deposited
JBrowse - Visual display of RNA-Seq signals
View Dmel\Marf1 in JBrowse2-54
2-55.3
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
Source for merge of: CG17018 CG17410
Source for merge of: CG17018 BcDNA:RE40762
Source for merge of CG17018 CG17410 was sequence comparison ( date:001216 ).
Source for merge of CG17018 BcDNA:RE40762 was a shared cDNA ( date:030728 ).
Source for identity of: Marf1 CG17018
The gene is named 'Marf1' based on the human ortholog.