FB2024_02 , released April 23, 2024
Gene Group - Macromolecular Complex: AUGMIN COMPLEX
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General Information
Name
AUGMIN COMPLEX
Species
D. melanogaster
Symbol
AUG
FlyBase ID
FBgg0001940
Date last reviewed
2024-01-25
Number of members
8
Description
Description
The augmin complex (known as homologous to augmin subunits (HAUS) complex in vertebrates) is an eight-subunit protein complex involved in the mitotic spindle assembly. The augmin complex acts as an adaptor, recruiting the gamma-tubulin ring complex (γ-TuRC) to existing spindle microtubules to nucleate branching to increase spindle density. (Adapted from PMID:36114186 and FBrf0235489.)
Notes on Group
Source Material
The AUGMIN COMPLEX Gene Group has been compiled using the following publication(s): Tariq et al., 2020 and Chen et al., 2017 .
Key Gene Ontology (GO) terms
Molecular Function
protein-macromolecule adaptor activity
Biological Process
mitotic spindle-templated microtubule nucleation
mitotic spindle assembly
Cellular Component
HAUS complex
Related Gene Groups
Protein Complex group(s)
GAMMA-TUBULIN RING COMPLEX
Members (8)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
dgt2
dim γ-tubulin 2
(Tariq et al., 2020, Chen et al., 2017)
dgt3
dim γ-tubulin 3
(Tariq et al., 2020, Chen et al., 2017)
dgt4
dim γ-tubulin 4
EG:EG0007.10
(Tariq et al., 2020, Chen et al., 2017)
dgt5
dim γ-tubulin 5
(Tariq et al., 2020, Chen et al., 2017)
dgt6
dim γ-tubulin 6
(Tariq et al., 2020, Chen et al., 2017)
msd1
mitotic spindle density 1
(Tariq et al., 2020, Chen et al., 2017)
msd5
mitotic spindle density 5
Dgt7
(Tariq et al., 2020, Chen et al., 2017)
wac
wee Augmin
Augmin
(Tariq et al., 2020, Chen et al., 2017)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
AUG
Homologous to AUgmin Subunits complex
HAUS
AUGMIN COMPLEX
Secondary FlyBase ID(s)
References (3)