FB2024_02 , released April 23, 2024
Gene Group - Macromolecular Complex: CHAT COMPLEX
Open Close
General Information
Name
CHAT COMPLEX
Species
D. melanogaster
Symbol
CHAT
FlyBase ID
FBgg0001749
Date last reviewed
Number of members
5
Description
Description
The chiffon histone acetyltransferase (CHAT) complex is a unique Gcn5 complex specific to insects that shows characteristic histone acetyltransferase activity towards histone H3. (Adapted from FBrf0241207, FBrf0247978 and FBrf0248705).
Notes on Group

In D.mel there are two splice isoforms of Ada2b and the short Ada2b isoform is the exclusive subunit of CHAT complex (FBrf0241207).

Source Material
The CHAT COMPLEX Gene Group has been compiled using the following publication(s): Helmlinger et al., 2021, Torres-Zelada and Weake, 2021, and Torres-Zelada et al., 2019 .
Key Gene Ontology (GO) terms
Molecular Function
histone acetyltransferase activity
Biological Process
regulation of transcription by RNA polymerase II
Cellular Component
Enzymatic activity
Enzyme name (EC)
histone acetyltransferase (2.3.1.48)
Related Gene Groups
Parent group(s)
GCN5-CONTAINING COMPLEXES
Protein Complex group(s)
ADA COMPLEX
ATAC COMPLEX
SAGA COMPLEX
Members (5)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Ada2b
transcriptional Adaptor 2b
dAda2b
(Helmlinger et al., 2021, Torres-Zelada and Weake, 2021, Torres-Zelada et al., 2019)
Ada3
transcriptional Adaptor 3
dAda3, dik, diskette
(Helmlinger et al., 2021, Torres-Zelada and Weake, 2021, Torres-Zelada et al., 2019)
chif
chiffon
BG:DS09218.1, Dbf4, BG:DS09218.2
(Helmlinger et al., 2021, Torres-Zelada and Weake, 2021, Torres-Zelada et al., 2019)
Gcn5
Gcn5 acetyltransferase
dGcn5, Pcaf, KAT, dmGCN5, dKAT2
(Helmlinger et al., 2021, Torres-Zelada and Weake, 2021, Torres-Zelada et al., 2019)
Sgf29
SAGA-associated factor 29kDa
dSgf29
(Helmlinger et al., 2021, Torres-Zelada and Weake, 2021, Torres-Zelada et al., 2019)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
CHAT
Chiffon histone acetyltransferase (CHAT) complex
CHAT COMPLEX
Secondary FlyBase ID(s)
References (4)