FB2024_02 , released April 23, 2024
Gene Group - Macromolecular Complex: NUCLEAR RNASE P COMPLEX
Open Close
General Information
Name
NUCLEAR RNASE P COMPLEX
Species
D. melanogaster
Symbol
RNASEP-N
FlyBase ID
FBgg0001675
Date last reviewed
2023-08-08
Number of members
10
Description
Description
Nuclear ribonuclease P (RNase P) is an essential endonuclease responsible for catalyzing 5' end maturation in precursor transfer RNAs (tRNAs) in the nucleus. It is a ribonucleoprotein (RNP) complex containing one conserved catalytic RNA subunit and a variable number of protein subunits - 8-10 in eukaryotes. (Adapted from PMID:27187488 and PMID:16998185.)
Notes on Group

Two homologues of Rpp14 (Rpp14a and Rpp14b) are present in D. melanogaster, located next to each other on chromosome 3R.

Source Material
The NUCLEAR RNASE P COMPLEX Gene Group has been compiled using the following publication(s): Palsule et al., 2019, Manivannan et al., 2015, Rosenblad et al., 2006, and Piccinelli et al., 2005 .
Key Gene Ontology (GO) terms
Molecular Function
ribonuclease P activity
Biological Process
tRNA 5'-end processing
Cellular Component
nucleolar ribonuclease P complex
Enzymatic activity
Enzyme name (EC)
ribonuclease P (3.1.26.5)
Related Gene Groups
Parent group(s)
RNASE P COMPLEXES
Protein Complex group(s)
RNASE MRP COMPLEX
Members (10)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Pop1
POP1 ribonuclease P/MRP subunit
l(1)G0045, BcDNA:LD21623, l(1)G0312
(Palsule et al., 2019, Rosenblad et al., 2006)
Pop4
POP4 ribonuclease P/MRP subunit
(Palsule et al., 2019, Rosenblad et al., 2006)
Pop5
POP5 ribonuclease P/MRP subunit
(Palsule et al., 2019, Rosenblad et al., 2006)
RNaseP:RNA
Ribonuclease P RNA
RNase P RNA
(Palsule et al., 2019, Manivannan et al., 2015, Piccinelli et al., 2005)
Rpp14a
Ribonuclease P/MRP subunit p14 a
Rpp14
(Palsule et al., 2019, Rosenblad et al., 2006)
Rpp14b
Ribonuclease P/MRP subunit p14 b
Rpp14
(Palsule et al., 2019, Rosenblad et al., 2006)
Rpp20
Ribonuclease P protein subunit p20
Pop7
(Palsule et al., 2019, Rosenblad et al., 2006)
Rpp21
Ribonuclease P/MRP subunit p21
Rpr2
(Palsule et al., 2019, Rosenblad et al., 2006)
Rpp25
Ribonuclease P/MRP subunit p25
(Palsule et al., 2019, Rosenblad et al., 2006)
Rpp30
RNaseP protein p30
l(2)k01901, coconut, Rpp1
(Palsule et al., 2019, Rosenblad et al., 2006)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
RNASEP-N
NUCLEAR RNASE P COMPLEX
Secondary FlyBase ID(s)
References (5)