Gene Group: SUPEROXIDE DISMUTASES

General Information

Name

SUPEROXIDE DISMUTASES

Species

D. melanogaster

Symbol

SOD

FlyBase ID

FBgg0001028

Date last reviewed

2022-10-10

Number of members

Description

Superoxide dismutase enzymes catalyze the breakdown of superoxide into hydrogen peroxide and water and are therefore central regulators of reactive oxygen species levels. (Adapted from FBrf0184132.)

Notes on Group

Sodq is omitted from this group because it is unlikely to have enzyme activity based on the absence of critical residues (FBrf0184132).

Rsod appears to be a member of an ancient group of proteins containing Cu/ZnSOD homology domains (FBrf0184132, FBrf0254615). It is included in this group, though its function is unknown.

Source Material

The SUPEROXIDE DISMUTASES Gene Group has been compiled using the following publication(s): Hewitt and Degnan, 2022, Blackney et al., 2014, and Landis and Tower, 2005 .

Key Gene Ontology (GO) terms

Molecular Function

superoxide dismutase activity

Biological Process

Cellular Component

Enzymatic activity

Enzyme name (EC)

superoxide dismutase (1.15.1.1)

Related Gene Groups

Parent group(s)

SUPEROXIDE RADICAL OXIDOREDUCTASES

Members (4)