The Epidermal Growth Factor Receptor (EGFR) signaling pathway is used multiple times during development (
FBrf0190321). It is activated by the binding of a secreted ligand to the receptor tyrosine kinase
Egfr and acts via the canonical Ras/Raf/MAP kinase (ERK) cascade. (Adapted from
FBrf0190321 and
FBrf0221727).