The Enhancer of split complex (E(spl)-C) of D.mel is a well characterized genetic locus on chromosome 3R containing 12 genes - with the exception of
Kaz-m1, all are Notch responsive. Seven genes are basic helix-loop-helix (bHLH) transcription factors, four are bearded family genes.
Kaz-m1 is unrelated, sharing some sequence similarity to Kazal class protease inhibitors. (Adapted from
FBrf0211195).