Replacement of the majority of the coding region (beginning near the start codon) of Dbct with a cassette containing attPX, two STOP codons and 3xP3-RFP.
abnormal locomotor behavior | larval stage
abnormal neuroanatomy | adult stage
decreased body size | pupal stage
increased cell death | larval stage
increased cell death | pupal stage
lethal
majority die during P-stage
partially lethal - majority die
short lived
some die during larval stage
adult brain
embryonic/larval brain | larval stage
embryonic/larval brain | pupal stage
DbctΔ heterozygous adults and escaper hemizygous adults are short lived.
DbctΔ heterozygous adults show brain vacuoles.
DbctΔ hemizygous larvae (DbctΔ/Y) show decreased crawling ability; the larval and pupal brains show increased apoptosis.