FB2024_02 , released April 23, 2024
Allele: Dmel\ddbtmCherry
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General Information
Symbol
Dmel\ddbtmCherry
Species
D. melanogaster
Name
FlyBase ID
FBal0322939
Feature type
allele
Associated gene
Dmel\ddbt
Associated Insertion(s)
Carried in Construct
P{mCherry-ddbt.WT}
Key Links
Transgenic product class
genomic_DNA
(Yamaki et al., 2016)
wild_type
(Yamaki et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Yamaki et al., 2016)
wild_type
(Yamaki et al., 2016)
Mutagen
in vitro construct - genomic fragment
(Yamaki et al., 2016)
in vitro construct - coding region fusion
(Yamaki et al., 2016)
Progenitor genotype
Carried in construct
P{mCherry-ddbt.WT}
Cytology
Description

3.84kb genomic fragment encompassing ddbt (derived from the CH322-142G7 BACPAC clone). Includes 1.69kb upstream and 1.45kb downstream sequence. The protein is tagged at the N-terminal end with mCherry.

(Yamaki et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
ddbt
Encoded product / tool
ddbt
Tagged with
mCherry
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      epitope tag
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage | male
      mid-late elongation-stage spermatid
      (Yamaki et al., 2016)
      late elongation-stage spermatid
      (Yamaki et al., 2016)
      individualization stage spermatid
      (Yamaki et al., 2016)
      spermatozoon
      (Yamaki et al., 2016)
      Additional Information
      Statement
      Reference

      Expression is observed during spermatogenesis in telomeres from mid-late enlongation-stage spermatids (comet-stage) on.

      (Yamaki et al., 2016)
       
      Marker for
      Reflects expression of
      ddbt
      (Yamaki et al., 2016)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      ddbtmCherry rescues ddbtZ4344

      (Yamaki et al., 2016)
      Comments

      The male sterility of ddbtZ4344 homozygous flies is rescued by combination with ddbtT:Disc\RFP-mCherry.

      (Yamaki et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ddbtT:Disc\RFP-mCherry
      ddbtmCherry
      Name Synonyms
      Secondary FlyBase IDs
        References (1)