FlyBase Allele Report: Dmel\Kah[QSR]

FB2024_04 , released June 25, 2024

FB2024_04 , released June 25, 2024

Allele: Dmel\Kah^QSR

General Information

Symbol

Dmel\Kah^QSR

Species

D. melanogaster

Name

FlyBase ID

FBal0295098

Feature type

allele

Associated gene

Associated Insertion(s)

Mi{Hto-WP}MED14^QSR

Carried in Construct

Key Links

Genomic Maps

Allele class

Mutagen

minos activity

Nature of the Allele

Allele class

Mutagen

(Singari et al., 2014)

Progenitor genotype

Associated Insertion(s)

Mi{Hto-WP}MED14^QSR

Cytology

Description

The Mi{Hto-WP}MED14^QSR insertion lies within the MED14 transcription unit. The insertion targets the downstream Kah gene (a protein-trap fusion protein can be overexpressed from the Scer\UAS sequences within the Mi{Hto-WP} element in the presence of a Scer\GAL4 driver).

(FlyBase, 1996-)

Allele components

Component

Use(s)

Inserted element

misexpression element

Regulatory region(s)

binary expression system - regulatory region

Tagged with

red fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:594,766..594,766 [-]

(Singari et al., 2014, FlyBase, 1996-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^GMR.PF

(Singari et al., 2014)

visible, with Scer\GAL4^pnr-MD237

(Singari et al., 2014)

Phenotype Manifest In

adult cuticle, with Scer\GAL4^pnr-MD237

(Singari et al., 2014)

adult thorax, with Scer\GAL4^pnr-MD237

(Singari et al., 2014)

chaeta, with Scer\GAL4^pnr-MD237

(Singari et al., 2014)

eye, with Scer\GAL4^GMR.PF

(Singari et al., 2014)

Detailed Description

Statement

Reference

Expression of Scer\GAL4^pnr-MD237>Kah^QSR in the thorax eliminates bristles leaving a stripe of naked cuticle.

(Singari et al., 2014)

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Kah^QSR, Scer\GAL4^pnr-MD237 has visible phenotype, non-enhanceable by mam^REM, Scer\GAL4^pnr-MD237

(Singari et al., 2014)

NOT suppressed by

Statement

Reference

Kah^QSR, Scer\GAL4^pnr-MD237 has visible phenotype, non-suppressible by mam^REM, Scer\GAL4^pnr-MD237

(Singari et al., 2014)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Kah^QSR, Scer\GAL4^pnr-MD237 has adult thorax phenotype, non-enhanceable by mam^REM, Scer\GAL4^pnr-MD237

(Singari et al., 2014)

Kah^QSR, Scer\GAL4^pnr-MD237 has adult cuticle phenotype, non-enhanceable by mam^REM, Scer\GAL4^pnr-MD237

(Singari et al., 2014)

Kah^QSR, Scer\GAL4^pnr-MD237 has chaeta phenotype, non-enhanceable by mam^REM, Scer\GAL4^pnr-MD237

(Singari et al., 2014)

NOT suppressed by

Statement

Reference

Kah^QSR, Scer\GAL4^pnr-MD237 has adult thorax phenotype, non-suppressible by mam^REM, Scer\GAL4^pnr-MD237

(Singari et al., 2014)

Kah^QSR, Scer\GAL4^pnr-MD237 has adult cuticle phenotype, non-suppressible by mam^REM, Scer\GAL4^pnr-MD237

(Singari et al., 2014)

Kah^QSR, Scer\GAL4^pnr-MD237 has chaeta phenotype, non-suppressible by mam^REM, Scer\GAL4^pnr-MD237

(Singari et al., 2014)

Additional Comments

Genetic Interactions

Statement

Reference

Flies co-expressing mam^REM and Kah^QSR both under the control of Scer\GAL4^pnr-MD237 display naked thoracic cuticle.

(Singari et al., 2014)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Kah^QSR

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections