FlyBase Allele Report: Dmel\Ask1[RNAi.UAS]

General Information

Symbol

Dmel\Ask1^RNAi.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0263921

Feature type

allele

Associated gene

Dmel\Ask1

Associated Insertion(s)

Carried in Construct

P{UAS-Ask1.RNAi}

Also Known As

UAS-DASK1-IR

Key Links

Transgenic product class

RNAi_reagent

(Sekine et al., 2011)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Sekine et al., 2011)

Mutagen

in vitro construct

(Sekine et al., 2011)

Progenitor genotype

Carried in construct

P{UAS-Ask1.RNAi}

Cytology

Description

UAS drives expression of a head-to-head inverted repeat of Ask1 cDNA (nt 1759-2257).

(Sekine et al., 2011)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Ask1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Ask1^RNAi.UAS, Scer\GAL4^pnr-MD237 is a non-enhancer of abnormal body color phenotype of Dhx15^GS11266, Scer\GAL4^pnr-MD237

(Mosallanejad et al., 2014)

Suppressor of

Statement

Reference

Ask1^RNAi.UAS, Scer\GAL4^pnr-MD237 is a suppressor | partially of abnormal body color phenotype of Scer\GAL4^pnr-MD237, slim^GS10238

(Sekine et al., 2012)

NOT Suppressor of

Statement

Reference

Ask1^RNAi.UAS, Scer\GAL4^pnr-MD237 is a non-suppressor of abnormal body color phenotype of Dhx15^GS11266, Scer\GAL4^pnr-MD237

(Mosallanejad et al., 2014)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Ask1^RNAi.UAS, Scer\GAL4^pnr-MD237 is a non-enhancer of adult cuticle phenotype of Dhx15^GS11266, Scer\GAL4^pnr-MD237

(Mosallanejad et al., 2014)

Suppressor of

Statement

Reference

Ask1^RNAi.UAS, Scer\GAL4^pnr-MD237 is a suppressor | partially of adult cuticle phenotype of Scer\GAL4^pnr-MD237, slim^GS10238

(Sekine et al., 2012)

NOT Suppressor of

Statement

Reference

Ask1^RNAi.UAS, Scer\GAL4^pnr-MD237 is a non-suppressor of adult cuticle phenotype of Dhx15^GS11266, Scer\GAL4^pnr-MD237

(Mosallanejad et al., 2014)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of Pk92B^{dsRNA.Scer\UAS} has no effect on the melanisation of the thorax seen in adults expressing Dhx15^GS11266 under the control of Scer\GAL4^pnr-MD237.

(Mosallanejad et al., 2014)

Co-expression of Mpk2^DN.Scer\UAS or lic^GD7546 partially suppresses the melanisation of the adult thorax cuticle seen in flies expressing slim^GS10238 under the control of Scer\GAL4^pnr-MD237.

(Sekine et al., 2012)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^pnr-MD237/Ask1^RNAi.UAS rescues Ask1^{ΔN.UAS.Tag:FLAG}

(Sekine et al., 2011)

Comments

Co-expression of Pk92B^{dsRNA.Scer\UAS} suppresses the pigmentation defect in Pk92B^{ΔN.Scer\UAS.T:Zzzz\FLAG}, Scer\GAL4^pnr-MD237 flies.

(Sekine et al., 2011)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Ask1^RNAi.UAS

Ask1^{dsRNA.Scer\UAS}

Ask1^dsRNA.UAS

Pk92B^{dsRNA.Scer\UAS}

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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