FB2024_03 , released June 25, 2024
Allele: Dmel\imd10191
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General Information
Symbol
Dmel\imd10191
Species
D. melanogaster
Name
FlyBase ID
FBal0243399
Feature type
allele
Associated gene
Dmel\imd
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        imd10191/imd10191 adult flies have a severely reduced survival after inoculation with either Providencia rettgeri or Enterococcus faecalis bacteria.

        (Chambers et al., 2014)

        Median survival in days is reduced in mutant flies compared to wild type.

        (Petersen et al., 2013)

        Mutant flies are highly susceptible to infection with either Providencia rettgeri or Providencia burhodogranariea.

        (Galac and Lazzaro, 2011)

        Homozygous flies are not more sensitive to Cricket Paralysis virus infection (after being injected with the virus) than control flies.

        (Costa et al., 2009)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        NOT Enhancer of
        Statement
        Reference

        imd10191 is a non-enhancer of short lived phenotype of tefuatm-8

        (Petersen et al., 2013)

        imd10191 is a non-enhancer of increased cell death | adult stage | semidominant phenotype of tefuatm-8

        (Petersen et al., 2013)
        NOT Suppressor of
        Statement
        Reference

        imd10191 is a non-suppressor of short lived phenotype of tefuatm-8

        (Petersen et al., 2013)

        imd10191 is a non-suppressor of increased cell death | semidominant | adult stage phenotype of tefuatm-8

        (Petersen et al., 2013)
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        References (9)