FlyBase Allele Report: Dmel\fwe[KK109356]

General Information

Symbol

Dmel\fwe^KK109356

Species

D. melanogaster

Name

FlyBase ID

FBal0236258

Feature type

allele

Associated gene

Dmel\fwe

Associated Insertion(s)

Carried in Construct

P{KK109356}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK109356}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK109356

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased cell death | larval stage, with Scer\GAL4^C-765

(Merino et al., 2022)

Phenotype Manifest In

wing disc | larval stage, with Scer\GAL4^C-765

(Merino et al., 2022)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^C-765/fwe^KK109356 is a suppressor of increased cell death | dominant | larval stage phenotype of magu²

(Merino et al., 2022)

Scer\GAL4^C-765/fwe^KK109356 is a suppressor of increased cell death | dominant | larval stage phenotype of dally^gem

(Merino et al., 2022)

Scer\GAL4^Act.PU/fwe^KK109356 is a suppressor of abnormal size | somatic clone | wandering third instar larval stage phenotype of Scer\GAL4^Act.PU, wupA^JF02172

(Casas-Tintó et al., 2016)

Scer\GAL4^Act.PU/fwe^KK109356 is a suppressor of increased cell death | somatic clone | wandering third instar larval stage phenotype of Scer\GAL4^Act.PU, wupA^JF02172

(Casas-Tintó et al., 2016)

Other

Statement

Reference

Scer\GAL4^C-765, fwe^KK109356, magu^UAS.EGFP has decreased cell death | larval stage phenotype

(Merino et al., 2022)

Scer\GAL4^C-765, dally^UAS.GFP, fwe^KK109356 has decreased cell death | larval stage phenotype

(Merino et al., 2022)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^C-765/fwe^KK109356 is a suppressor of wing disc | larval stage phenotype of magu²

(Merino et al., 2022)

Scer\GAL4^C-765/fwe^KK109356 is a suppressor of wing disc | larval stage phenotype of dally^gem

(Merino et al., 2022)

Scer\GAL4^Act.PU/fwe^KK109356 is a suppressor of wing disc | somatic clone | wandering third instar larval stage phenotype of Scer\GAL4^Act.PU, wupA^JF02172

(Casas-Tintó et al., 2016)

Other

Statement

Reference

Scer\GAL4^C-765, fwe^KK109356, magu^UAS.EGFP has wing disc | larval stage phenotype

(Merino et al., 2022)

Scer\GAL4^C-765, dally^UAS.GFP, fwe^KK109356 has wing disc | larval stage phenotype

(Merino et al., 2022)

Additional Comments

Genetic Interactions

Statement

Reference

The co-expression of fwe^KK109356 suppresses the increased apoptosis and the decreased relative clonal area of somatic clones expressing wupA^JF02172 under the control of Scer\GAL4^Act.PU in wandering third instar larval wing discs.

(Casas-Tintó et al., 2016)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v104993

P{KK109356}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

CG6151^KK109356

flower^KK109356

fwe^KK109356

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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