FB2024_04 , released June 25, 2024
Allele: Dmel\sogP1
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General Information
Symbol
Dmel\sogP1
Species
D. melanogaster
Name
FlyBase ID
FBal0039965
Feature type
allele
Associated gene
Dmel\sog
Associated Insertion(s)
P{dpn-lacZ.dA}sogP1
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Serpe et al., 2005, Francois et al., 1994)
Mutagen
P-element activity
(Francois et al., 1994)
Progenitor genotype
Associated Insertion(s)
P{dpn-lacZ.dA}sogP1
Cytology
Description

Insertion of a P-element carrying a dpn promoter-Ecol\lacZ fusion about 170bp within the 5' end of the transcription unit.

(Francois et al., 1994)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Only 12% of sogP129D/sogP1 transheterozygotes survive to adulthood and 46% of these exhibit various degrees of loss of the posterior crossvein.

      (Serpe et al., 2005)

      Clones that span the wing veins cause the vein to meander about their normal trajectories and vary in thickness.

      (Yu et al., 1996)

      Hemizygous embryos die with a cuticle phenotype.

      (Francois et al., 1994)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Excision of the P-element reverts the phenotype to wild type. sogP1 allows some rescue haplo-insufficiency of dpp.

      (Francois et al., 1994)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      sogP1
      Name Synonyms
      Secondary FlyBase IDs
        References (5)