FlyBase Allele Report: Dmel\cp[1]

General Information

Symbol

Dmel\cp¹

Species

D. melanogaster

Name

FlyBase ID

FBal0001793

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Also Known As

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

wing

Detailed Description

Statement

Reference

Shows partial dominance in combination with Minutes.

(Sinclair and Suzuki, 1979)

Wing margins snipped, most often along marginal vein. At 19^oC, character slighter but completely penetrant. Most stocks carry closely linked modifiers. Has reduced viability when phenotype is good (Craymer). RK2.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

M(3)80¹, cp[+]/cp¹ has visible | dominant | heat sensitive phenotype

(Sinclair et al., 1984, Sinclair et al., 1981)

cp¹, su(f)⁸ has visible | dominant | heat sensitive phenotype

(Sinclair et al., 1984)

Ybb^ts1, cp¹ has visible | dominant phenotype

(Sinclair et al., 1984)

cp[+]/cp¹, su(f)⁸ has visible | heat sensitive phenotype

(Sinclair et al., 1984)

M(3)80¹, cp[+]/cp¹ has partially lethal | dominant | heat sensitive phenotype

(Sinclair et al., 1984)

Ybb^ts1, cp[+]/cp¹ has visible phenotype

(Sinclair et al., 1984)

M(3)80¹, cp¹ has visible | dominant | heat sensitive phenotype

(Sinclair et al., 1984)

M(3)80[+]/M(3)80¹, cp¹ has visible | dominant | heat sensitive phenotype

(Sinclair et al., 1981)

M(3)80[+]/M(3)80¹, cp¹ has partially lethal | dominant | heat sensitive phenotype

(Sinclair et al., 1981)

cp¹, su(f)⁸/su(f)[+] has visible | dominant | heat sensitive phenotype

(Sinclair et al., 1981)

Phenotype Manifest In

NOT suppressed by

Statement

Reference

cp¹ has phenotype, non-suppressible by su(Hw)²

(Lindsley and Grell, 1968)

Other

Statement

Reference

M(3)80¹, cp[+]/cp¹ has wing margin | posterior phenotype

(Sinclair et al., 1984)

cp¹, su(f)⁸ has wing phenotype

(Sinclair et al., 1984)

cp¹, su(f)⁸ has adult cuticle phenotype

(Sinclair et al., 1984)

Ybb^ts1, cp¹ has wing phenotype

(Sinclair et al., 1984)

cp[+]/cp¹, su(f)⁸ has macrochaeta phenotype

(Sinclair et al., 1984)

cp[+]/cp¹, su(f)⁸ has wing phenotype

(Sinclair et al., 1984)

cp[+]/cp¹, su(f)⁸ has adult cuticle phenotype

(Sinclair et al., 1984)

Ybb^ts1, cp[+]/cp¹ has wing phenotype

(Sinclair et al., 1984)

M(3)80¹, cp¹ has wing | posterior phenotype

(Sinclair et al., 1984)

cp¹, su(f)⁸ has macrochaeta phenotype

(Sinclair et al., 1984)

M(3)80¹, cp[+]/cp¹ has wing phenotype

(Sinclair et al., 1981)

M(3)80[+]/M(3)80¹, cp¹ has wing | posterior phenotype

(Sinclair et al., 1981)

Additional Comments

Genetic Interactions

Statement

Reference

cp¹/M(3)80¹ heterozygotes are normal at 22^oC. At 29^oC they have reduced viability and have nicks in the posterior margin of the wing. su(f)⁸/Y ; cp¹/+ flies are normal at 22^oC. At 28^oC they have nicked wings and show a bb-like phenotype, having small bristles, slow development and cuticular defects. Ybb^ts1; cp¹/+ flies have nicked wings at 22^oC.

(Sinclair et al., 1984)

The cp¹ wing phenotype is enhanced by M(2)56F^unspecified. cp¹/+ ; M(3)80¹/+ flies show no novel phenotypes at 22^oC, but at 29^oC they show nicks in the posterior wing margin.

(Sinclair et al., 1981)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

cp^I5

(Lukinova et al., 1999)

Comments

Images (1)

Holtzman, S. and Kaufman, T. (2013)

Mutant