FB2024_04 , released June 25, 2024
Aberration: Dmel\Df(2L)BSC37
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General Information
Symbol
Df(2L)BSC37
Species
D. melanogaster
Name
FlyBase ID
FBab0037634
Feature type
chromosomal_deletion
Computed Breakpoints include
Features within 22D1--22F2
Genomic Maps
Sequence coordinates
2L:2,175,620..2,175,620 (Df(2L)BSC37:bk1)
(Cook, 2016.2.8)
2L:2,450,829..2,450,829 (Df(2L)BSC37:bk2)
(Cook, 2016.2.8)
Member of large scale dataset(s)
Dfs_BSC_set1

A set of ~50 targeted deficiencies created by exploiting hybrid element insertion (HEI) and resolution; designed to fill gaps in deletion coverage.

(Parks et al., 2004)
Nature of Aberration
Cytological Order
Progenitor
P{PZ}aop03953a
(Parks et al., 2004, Deal et al., 2003.7.22)
P{EP}dppEP2232
(Parks et al., 2004, Deal et al., 2003.7.22)
Mutagen
Delta2-3 transposase
(Deal et al., 2003.7.22)
recombination
(Deal et al., 2003.7.22)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Parks et al., 2004, Deal et al., 2003.7.22)
Breakpoints

22D1-22D3;22F1-22F2

(Parks et al., 2004, Deal et al., 2003.7.22)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

The 2L:2175620 release 6 coordinate of the left breakpoint is an estimate. It corresponds to the insertion site of P{PZ}aop03953a. As FBrf0175003 explains, deletions generated by P transposase in the presence of trans-heterozygous P elements are expected to extend from the end of one P insertion to the vicinity of the other P insertion.

(Cook, 2016.2.8)

The 2L:2450829 release 6 coordinate of the left breakpoint is an estimate. It corresponds to the insertion site of P{EP}dppEP2232. As FBrf0175003 explains, deletions generated by P transposase in the presence of trans-heterozygous P elements are expected to extend from the end of one P insertion to the vicinity of the other P insertion. It is unlikely sequences to the right of P{EP}dppEP2232 are deleted, because dpp is haplolethal.

(Cook, 2016.2.8)
Comments on Cytology

Distal break between 22D1 and the 22D3,4 doublet; proximal break within the 22F1,2 doublet.

(Deal et al., 2003.7.22)
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
eys
(Husain et al., 2006)
Rab5
(Deal et al., 2003.7.22)
Sec24CD
(Forster et al., 2010)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
diehard1
(Lee, 2012)
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
Phenotypic Data
In combination with other aberrations

Df(2L)OK371Δ fails to complement Df(2L)BSC37.

(Mahr and Aberle, 2006)

Inferred to overlap with: Df(2L)OK371Delta.

(Mahr and Aberle, 2006)
NOT in combination with other aberrations
Stocks (2)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 

The deficiency chromosome retains the miniwhite marker from P{EP}dppEP2232.

(Mason, 2004.11.26)
Synonyms and Secondary IDs (3)
References (17)