[66D12-66D12];[66E6-66E6];
A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial core set of 209 isogenic deletions provides ~60% euchromatic genome coverage.
66D12;66E6
This deletion removes a single ribosomal protein-coding gene (though other genes are also removed).
Df(3L)knittrigΔ1 embryos transheterozygous with Df(3L)ED4413 show reduced formation of ganglionic tracheal branches with significant penetrance - the majority of embryos show disruption in at least one ganglionic branch. No abnormal phenotype is detected for midline glial cells.
Df(3L)knittrigΔ1 flies transheterozygous with Df(3L)ED4413 show reduced viability and only rare escaper flies are found. Most mutants die during pupal stages or as pharate adults. Most escapers are unable to undergo complete wing inflation, causing wrinkled wings. Some escapers show partially inflated and abnormally opaque wings. Mutant pupal wings appar normal.
Flies heterozygous for the deletion do not show a Minute bristle phenotype.
Potential deficiency; could be generated as the recombinant product between the reduced derivatives of P{RS5}5-SZ-3482 and P{RS3}CB-5216-3.
Limits of break 1 computationally determined from location of progenitor P insertion on genome sequence between P{PZ}SrpRβrK561&P{lacW}l(3)j5B6j5B6 and P{PZ}l(3)0162901629&P{PZ}mRpL1210534 Limits of break 2 computationally determined from location of progenitor P insertion on genome sequence between P{PZ}l(3)0162901629&P{PZ}mRpL1210534 and P{EP}Hsp26EP3336&P{EP}Hsp26EP3315