FB2024_03 , released June 25, 2024
Aberration: Dmel\Tp(1;1)f+ih
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General Information
Symbol
Tp(1;1)f+ih
Species
D. melanogaster
Name
Transposition (1;1) forked-wild type in heterochromatin
FlyBase ID
FBab0021550
Feature type
intrachromosomal_transposition
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
Class of aberration (relative to wild type)
intrachromosomal_transposition
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
fX
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

The inserted segment contains the entire 40 kb walk of McLachlan.

Comments on Cytology

Polytene chromosomes apparently normal (J.I. Valencia).

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    "f[m]" flies (fX Tp(1;1)f+ih double mutant) show a variable phenotype; many have an ordinary f mutant phenotype, but a high percentage show coherent patches of the body, often of considerable size, in which the bristles are normal. Occasionally, almost the whole fly appears wild type.

    (Muller, 1946)

    Tp(1;1)f+ih with any f allele has normalizing effect. Patches of bristles and occasionally whole fly is wild type. An extra Y chromosome enhances the normalizing effect.

    Stocks (0)
    Notes on Origin
    Discoverer

    Muller.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    f[X] plus Tp(1;1)f[+ih] denoted "f[m]: forked-mottled". Apparently, Tp(1;1)f+ih is all or part of the normal allele of f transposed to the proximal heterochromatin of the X chromosome, where it variegates. The sequences remaining in the original position behave as a hypomorph of f, fX. Oster, Erlich and Muller (1957) argue that the sum of sequences inserted in the heterochromatin plus those remaining behind exceeds the normal sequential content of f[+].

    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    Tp(1;1)f+ih
    f+ih
    Name Synonyms
    Transposition (1;1) forked-wild type in heterochromatin
    Secondary FlyBase IDs
    • FBal0003966
    References (6)