FB2024_03 , released June 25, 2024
Aberration: Dmel\T(1;2)scS2
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General Information
Symbol
T(1;2)scS2
Species
D. melanogaster
Name
Translocation (1;2) scute of Sinitskaya
FlyBase ID
FBab0006147
Feature type
chromosomal_translocation
Computed Breakpoints include

1B4;60E6-60E8

Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to wild type)
chromosomal_translocation
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_translocation
(Ludwig et al., 1991, Lindsley and Grell, 1968)
Breakpoints

1B4-1B7;60C-60E

(Lindsley and Grell, 1968)

[];60E6--8

(Sunkel and Whittle, 1987)

1B4-1B7;60E6-60E8

(Ludwig et al., 1991)
Causes alleles
scS2
(Gomez-Skarmeta et al., 1995, Lindsley and Zimm, 1992)
Carries alleles
Transposon Insertions
Formalized genetic data

l(1)sc << bk1 << sc << sp << bk2 << RpL19

Genetic mapping information
Comments

Breakpoint(s) molecularly mapped

(Cohen et al., 1989)

3.0 to 4.4kb DNA is deleted in the neighbourhood of the first chromosome breakpoint.

(Campuzano et al., 1985)

X breakpoint between left breakpoints of In(1)sc9 and In(1)sc7 (Campuzano, Carramolino, Cabrera, Ruiz-Gomez, Villares, Bononat and Modell, 1985, Cell 49: 327-38).

Comments on Cytology

Cytology inferred from genetic results.

(Lindsley and Grell, 1968)

Left limit of break 1 from polytene analysis (FBrf0042024) Right limit of break 1 from complementation mapping against sc (FBrf0042024) Limits of break 2 from polytene analysis (FBrf0047276)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
sc
(Campuzano et al., 1985)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Dll
(Sunkel and Whittle, 1987)
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    When males with Dp(1;1)Co are crossed with T(1;2)scS2 females, and somatic clones are induced (in the wing disc) with a FRT site at 18A, clones with cells containing 4 copies of dm (2 endogenous and 2 from the tandem duplication in Dp(1;1)Co) and heterozygous for RpL19 (due to missing one copy of RpL19 on Ts(1Lt;2Lt)scS2). These clones are unable to out-compete surrounding cells and are eliminated.

    (Moreno and Basler, 2004)
    NOT in combination with other aberrations

    Homozygous females show an almost complete loss of tergite chaetae.

    (Mari-Beffa et al., 1991)
    Stocks (4)
    Notes on Origin
    Discoverer

    Sinitskaya, 1934.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
    Other Comments
     
    Synonyms and Secondary IDs (5)
    Reported As
    Symbol Synonym
    T(1,2)scs2
    (Moreno et al., 2002)
    T(1;2)sc-S2
    T(1;2)scS2
    scS2
    (Mari-Beffa et al., 1991)
    Name Synonyms
    Translocation (1;2) scute of Sinitskaya
    Secondary FlyBase IDs
      References (13)