FB2024_03 , released June 25, 2024
Aberration: Dmel\In(1)scL8
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General Information
Symbol
In(1)scL8
Species
D. melanogaster
Name
Inversion (1) scute of Levy
FlyBase ID
FBab0004211
Feature type
chromosomal_inversion
Computed Breakpoints include

1B3-1B4;20B-20C

Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to wild type)
chromosomal_inversion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_inversion
(Slobodyanyuk and Serov, 1983, Lindsley and Grell, 1968)
Breakpoints

1B3-1B4;20B-20C

(Slobodyanyuk and Serov, 1983, Lindsley and Grell, 1968)
Causes alleles
scL8
(Lindsley and Zimm, 1992, Campuzano et al., 1985)
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 hits sc << bk2 << ABO-X

Genetic mapping information
Comments

Breakpoint(s) molecularly mapped

(Campuzano et al., 1985, Carramolino et al., 1982)

Breakpoint between DNA coordinates +30.9 and +28.8 (Campuzano et al., 1985). 0 is an arbitrarily chosen EcoRI site in the scĪ² segment of ASC; positive values to the left (Carramolino et al., 1982).

Comments on Cytology

Cytology inferred from genetic data.

(Lindsley and Grell, 1968)

Limits of break 1 from polytene analysis (FBrf0039957) Limits of break 2 from polytene analysis (FBrf0042024)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
sc
(Campuzano et al., 1985)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Lethality of In(1)scL8/0 males can be suppressed by maternal effect.

    (Johnson et al., 1979)

    In gynandromorphs, however, In(1)scL8/0 cells viable and normal in appearance suggesting that position effect suppression of rRNA is non-autonomous.

    (Pyati, 1976)

    Homozygous females are sterile. In(1)scL8/0 almost completely male lethal.

    (Puckett and Snyder, 1973)

    In(1)scL8/0 almost completely male lethal. Lethality believed to be due to position-effect inactivation of the ribosomal cistrons and other genes affecting viability.

    (Baker, 1971)
    Stocks (1)
    Notes on Origin
    Discoverer

    Levy, 1932.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (4)
    Reported As
    Symbol Synonym
    In(1)scL8
    In(1)scL8
    (Johnson et al., 1979)
    scL8
    (Slobodyanyuk and Serov, 1983)
    Name Synonyms
    Inversion (1) scute of Levy
    Secondary FlyBase IDs
      References (16)